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目的了解院内ICU患者深部真菌感染的临床和病原学特点。方法在2006年1月至2008年1月期间,对217例ICU患者进行前瞻性研究。结果2年期间ICU共分离出29株真菌,以白色念珠菌和热带念珠菌为主,其发生与2种以上广谱抗生素联合运用,糖皮质激素的使用,导尿管、气管插管和深静脉留置针的使用有关。结论警惕上述ICU患者深部真菌感染的相关危险因素对临床防治深部真菌病具有重要意义。
Objective To understand the clinical and etiological characteristics of deep fungal infections in hospital ICU patients. Methods From January 2006 to January 2008, 217 ICU patients were prospectively studied. Results A total of 29 strains of fungi were isolated from the ICU in two years. They were mainly Candida albicans and Candida tropicalis. They were used in combination with two or more broad-spectrum antibiotics. The use of glucocorticoids, catheters, endotracheal intubation and deep Vein indwelling needle use related. Conclusion It is important to guard against the risk factors associated with deep fungal infection in ICU patients mentioned above for the prevention and treatment of deep mycosis.