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目的 研究不同年龄组重症肌无力 ( MG)患者的临床特点及疗效。方法 将 68例MG患者按不同年龄分为少儿期 MG、青年期 MG和中老年期 MG三组 ,对其临床资料进行统计学分析比较。结果 少儿组以胸腺增生为主 ( 10 / 11例 ) ,较其余两组有显著性差异 ( P<0 .0 1)且手术治疗效果好 ,无合并症。青年组胸脉增生 ( 14/ 2 8)较中老年组多 ( P<0 .0 1) ,合并其他免疫性疾病多见。中老年组胸腺增生 7例 ,胸腺瘤 8例 ( 4例恶性 )较青年组多 ( P<0 .0 1)且药物及手术治疗预后差。结论 不同年龄组 MG患者的临床分型及病理类型不同 ,导致治疗及预后不
Objective To study the clinical features and therapeutic effects of myasthenia gravis (MG) in different age groups. Methods Sixty-eight patients with MG were divided into three groups according to different ages: young MG, young MG and middle-aged MG. The clinical data were statistically analyzed and compared. Results Thymus hyperplasia was the most common group (10/11 cases), which was significantly different from the other two groups (P <0.01). The surgical treatment was effective and no complications were found. Thoracic hyperplasia (14/28) in the youth group was more than that in the middle-aged and elderly group (P <0.01), and other immunologic diseases were more common. 7 cases of thymus hyperplasia and 8 cases of thymoma (4 cases of malignant) in the middle and old age group were more than those in the young group (P <0.01), and the prognosis of the drug and operation was poor. Conclusion The clinical types and pathological types of patients with MG in different age groups are different, leading to not treatment and prognosis