论文部分内容阅读
四环素类药物杀灭恶性疟原虫裂殖体的作用缓慢,需先服短程的奎宁,以迅速降低患者的疟原虫血症。四环素或二甲氨四环素配伍奎宁能治愈抗氯喹的恶性疟疾。Powers等(1972)发现7-氯林可霉素(Clindamycin)能治愈感染对多种药物有抗性的恶性疟原虫的夜猴,并认为对人的恶性疟亦可能有效。本文作者对7-氯林可霉素配伍奎宁治疗人体恶性疟的效果进行了临床试验。以感染柬埔寨Ⅰ株、巴拿马Ⅱ株及缅甸Thau株恶性疟原虫者为治疗观察对象。在感染者血内原虫密度未超过10,000个/立方毫米时分组采用下列方案进行治疗:第1组4例,包括感染柬埔寨Ⅰ株者3例,缅甸Thau
Tetracyclines kill the P. falciparum Schizonts slow role, need to take a short range of quinine, in order to rapidly reduce the patient’s Plasmodium. Tetracycline or dimethylamin tetracycline compatibility quinine can cure chloroquine-resistant malignant malaria. Powers et al. (1972) found that 7-Clindamycin can cure cows infected with Plasmodium falciparum that is resistant to many drugs and that it may be effective against human falciparum malaria. The authors conducted a clinical trial of the efficacy of 7-clindamycin combined with quinine in the treatment of human falciparum malaria. Infection with Cambodia Ⅰ strain, Panama Ⅱ strain and Myanmar Thau strain of Plasmodium falciparum were the treatment of the object of observation. In the infected blood protozoa density did not exceed 10,000 / mm3 when subgroups were treated with the following scheme: Group 1 4 cases, including infection in Cambodia Ⅰ 3 cases, Myanmar Thau