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本文采用亲合酶标法,对50例卵巢上皮癌作雌激素受体(ER),孕激素受体检测(PR),阳性细胞百分率经半定量测定(大于20%者为阳性病例)小于者为阴性病例。结果显示ER阳性32例(64%),PR阳性24例(48%)。其中ER与PR均阳性19例(38%),只有ER阳性13例(26%)及PR阳性5例(10%)。提示阳性病例肿瘤细胞的功能尚未完全丧失,内分泌治疗可能会有一定反应。病检同时测定受体含量,有助于区分肿瘤的分化程度,并提供临床决定是否选用内分泌治疗,为临床研究提供有益的参考。
In this study, 50 cases of epithelial ovarian cancer were tested for estrogen receptor (ER) and progesterone receptor (PR) by affinity enzyme labeling method. The percentage of positive cells by semi-quantitative determination (> 20% positive cases) Negative cases. The results showed that ER positive in 32 cases (64%), PR positive in 24 cases (48%). There were 19 cases (38%) positive for ER and PR, only 13 cases (26%) were ER positive and 5 cases (10%) were PR positive. Prompt positive cases of tumor cells have not yet completely lost the function, endocrine therapy may have some response. Pathological examination at the same time determine the receptor content, contribute to differentiate the degree of tumor differentiation, and provide clinical decisions whether to use endocrine therapy for clinical research provide a useful reference.