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非溃疡性消化不良(non-ulcer dyspepsia,NUD)又称功能性消化不良(functional dyspepsia,FD)约占消化不良的40～60％,发病率高。现已证实NUD主要病因为上消化道运动功能障碍所致。NUD患者有无胃酸分泌障碍尚有争议。为探讨NUD与胃酸分泌的关系,本文对58例NUD患者作空腹血浆胃泌素检测,并对其中服用普瑞博思4周的22例作治疗前后对比观察,现报道如下。 1 资料和方法 NUD组58例,其中男27例,女31例,平均年龄46岁。均表现为不同程度的上腹部不适或疼痛、腹胀、早饱、嗳气、恶心、呕吐、泛酸及烧心感等消化
Non-ulcer dyspepsia (NUD), also known as functional dyspepsia (FD) accounts for 40 to 60% of indigestion, the incidence of high. It has been confirmed that the main cause of NUD is caused by upper gastrointestinal motility disorders. NUD patients with or without gastric acid secretion disorder is still controversial. In order to explore the relationship between NUD and gastric acid secretion, this article 58 cases of NUD patients for fasting plasma gastrin test, and taking 4 weeks of pregabalin in 22 cases for comparison before and after treatment, are reported below. 1 Materials and Methods NUD group of 58 patients, including 27 males and 31 females, mean age 46 years. All showed varying degrees of upper abdominal discomfort or pain, bloating, early fullness, belching, nausea, vomiting, pantothenic acid and heartburn and other digestion