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16～19世纪的英国,尤其是在终年不见阳光的“雾都”伦敦,很多工业区随处都可以看到由于佝偻病而致残的儿童,这些孩子从婴儿时期就出现方颅、肋串珠、鸡胸或漏斗胸,年纪再大些,由于骨质软化,出现膝内翻或膝外翻(即俗称的O形或X形腿),严重者甚至会影响行走功能。但是在很长的一段时间里,人们都不清楚这种可怕的疾病到底是什么原因引起的。
In the 16th to 19th centuries, especially in the foggy city of London, where there is no sunshine all year round, many children with orphaned as a result of rickets can be seen in many industrial areas. These children emerged from infancy as square skull, rib beaded, and chicken breast Or funnel chest, older and then older, due to bone softening, there knee varus or knee valgus (commonly known as O-shaped or X-shaped legs), severe cases can even affect the walking function. But for a long time, people did not know exactly what caused this terrible disease.