论文部分内容阅读
目的了解武汉地区丙型肝炎病毒(HCV)流行病学特性,对HCV感染采取有效的预防和控制策略提供科学的理论依据。方法收集2011年1月—2015年12月武汉大学人民医院检验科进行抗-HCV筛查的人群基本信息,并记录抗-HCV,HCV-RNA载量和HCV基因型结果。结果 2011—2015年间HCV感染率比较,差异无统计学意义(χ2=2.94,P=0.568)。各年龄段的男女感染率比较,差异有统计学意义(χ2=76.00,P<0.01)。男性HCV感染者各年龄段抗-HCV水平间比较,差异无统计学意义(F=1.06,P=0.390);而女性HCV感染者各年龄段抗-HCV水平间比较,差异有统计学意义(F=4.67,P<0.01)。武汉地区以1 b基因型最多(71.98%),2 a型次之(17.14%),未发现4、5型基因。结论 HCV感染与年龄和性别具有一定关系。
Objective To understand the epidemiological characteristics of hepatitis C virus (HCV) in Wuhan and to provide a scientific theoretical basis for effective prevention and control strategies for HCV infection. Methods The basic information of anti-HCV screening population from January 2011 to December 2015 in Department of Laboratory Medicine of People’s Hospital of Wuhan University was collected and the results of anti-HCV, HCV-RNA load and HCV genotype were recorded. Results There was no significant difference in the prevalence of HCV infection between 2011 and 2015 (χ2 = 2.94, P = 0.568). The infection rates of men and women in all age groups were significantly different (χ2 = 76.00, P <0.01). There was no significant difference in anti-HCV level between men and women with HCV infection at all ages (F = 1.06, P = 0.390). However, there was significant difference in anti-HCV level between women with HCV infection and other age groups F = 4.67, P <0.01). In Wuhan, 1 b genotype was the most (71.98%), followed by 2 a (17.14%), and no type 4 and 5 genes were found. Conclusion HCV infection has some relationship with age and gender.