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目的观察大剂量免疫球蛋白治疗伴免疫异常的神经系统疾病的效果。方法予患者静注大剂量人血免疫球蛋白，记录治疗后不同时间内的病情变化、体征和有关辅助检查。结果静注免疫球蛋白对重症肌无力、多发性硬化、多数单神经病、多发性肌炎、Takayasu病及难治性癫痫疗效好，特别是对重症肌无力伴呼吸和吞咽麻痹有快速改善症状的作用，还可对抗由肾上腺皮质激素减量引起的反跳作用；对运动神经元病和小脑变性无效。结论静注免疫球蛋白对神经系统自身免疫性疾病和与免疫反应有关的疾病疗效好，对变性或遗传病疗效不佳或无效。
Objective To observe the effect of high-dose immunoglobulin in the treatment of neurological diseases with immunological abnormalities. Methods To patients with high-dose intravenous injection of human immunoglobulin, recording changes in condition at different times after treatment, signs and related auxiliary examination. Results Intravenous immunoglobulin was effective in treating myasthenia gravis, multiple sclerosis, most mononeuropathy, polymyositis, Takayasu disease and refractory epilepsy, especially for those patients with myasthenia gravis with rapid improvement of respiratory and swallowing paralysis Role, but also against the rebound caused by the adrenal cortex hormone reduction; motor neuron disease and cerebellar degeneration invalid. Conclusion Intravenous immunoglobulin has good curative effect on neurological autoimmune diseases and immune reaction-related diseases, and is ineffective or ineffective on degenerative or genetic diseases.