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目的:探讨高原地区HP感染的4种根除方案效果。方法:94例HP阳性患者随机分为4组,每组采用不同的治疗方案,每个治疗方案15天为一个疗程,治疗结束后5周复查。结果:阿莫西林+呋喃唑酮+奥美拉唑三联用药方案组和阿莫西林+呋喃唑酮+雷尼替丁+德诺四联用药方案组优于雷尼替丁+甲硝唑+四环素三联用药方案组和单一用药方案组;雷尼替丁+甲硝唑+四环素三联用药方案组药物不良反应较大。结论:在高原地区采用阿莫西林+呋喃唑酮+奥美拉唑三联用药对根除HP感染和溃疡愈合有较好疗效。
Objective: To investigate the effect of four kinds of eradication programs on HP infection in plateau. Methods: Ninety-four patients with positive HP were randomly divided into four groups with different treatment regimens. Each treatment regimen was a course of 15 days and was reviewed 5 weeks after the end of treatment. Results: The amoxicillin + furazolidone + omeprazole triple combination regimen group and amoxicillin + furazolidone + ranitidine + de novo quadruple drug regimen group was superior to ranitidine + metronidazole + tetracycline triple regimen Group and a single drug regimen group; ranitidine + metronidazole + tetracycline triple drug group adverse drug reactions larger. Conclusion: The combination of amoxicillin + furazolidone + omeprazole in the plateau region has a good effect on eradicating HP infection and ulcer healing.