Diagnostic Power of Diffusion-weighted Magnetic Resonance Imaging for the Presence of Lymph Node Met

• 作 者: Xiang-chuang KONG Ling-yun XIONG Emre Gazyakan Holger Engel Ulrich Kneser Andreas K.Nüssler Christoph Hirche Xiang-quan KONG
• 机 构: Department of Radiology, Union Hospital, Tongji Medical College,Huazhong University of Science and T
• 出 处: 华中科技大学学报（医学英德文版）
• 发表日期: 2017年4期
• 关键词: Meta-analysis magnetic resonance imaging lymph node metastasis diffusion-weighte

Present work was designed to quantitatively evaluate the performance of diffusion-weighted magnetic resonance imaging (DWI) in the diagnosis of the presence of metastasis in lymph nodes (LNs).Eligible studies were identified from systematical PubMed and EMBASE searches.Data were extracted.Meta-analyses were performed to generate pooled sensitivity and specificity on the basis of per-node,per-lesion and per-patient,respectively.Fourteen publications (2458 LNs,404 lesions and 334 patients) were eligible.Per-node basis demonstrated the pooled sensitivity and specificity was 0.82 (P＜0.0001) and 0.90 (P＜0.0001),respectively.Per-lesion basis illustrated the pooled sensitivity and specificity was 0.73 (P=-0.0036) and 0.85 (P＜0.0001),respectively.Per-patient basis indicated the pooled sensitivity and specificity was 0.67 (P=0.0909) and 0.86 (P＜0.0001),respectively.In conclusion,DWI has rather a negative predictive value for the diagnosis of LN metastasis presence.The difference of the mean apparent diffusion coefficients between benign and malignant LNs is not yet stable.Therefore,the DWI technique has to be further improved.