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目的:评价使用妈富隆口服避孕药和元宫药铜220型宫内节育器对已婚育龄妇女血红蛋白的影响。方法:采用前瞻性队列研究方法,对870例使用妈富隆和1 119例放置元宫药铜220的妇女进行健康筛查和随访,了解不良反应发生情况,比较避孕方法使用前、使用后6个月、12个月血红蛋白浓度的变化。结果:使用妈富隆后12个月内妇女经期延长/经量增多的发生率低于元宫药铜220使用者(P<0.01)。和使用前相比,使用妈富隆6个月、12个月的平均血红蛋白浓度逐渐升高,差异有统计学意义(P<0.01),而使用元宫药铜220后,平均血红蛋白浓度差异无统计学意义。结论:使用妈富隆口服避孕药后出血不良反应发生较少,能有效防止育龄妇女缺铁性贫血的发生。
Objective: To evaluate the effect of Marvelon Oral Contraceptives and Yuan Gong Medicine Copper-220 IUD on hemoglobin in married women of childbearing age. Methods: A prospective cohort study was conducted to evaluate the adverse effects of 870 women using Marvelon and 1119 women with uterotonic bronze 220. Six pre-contraception methods were used before and after contraception Month, 12 months hemoglobin concentration changes. Results: The incidence of menstrual prolongation / menstrual flow in women within 12 months after using marvelon was lower than that of uterine drug copper 220 (P <0.01). Compared with before use, using Marvelon 6 months, 12-month average hemoglobin concentration gradually increased, the difference was statistically significant (P <0.01), and the use of uterine copper 220, the average difference was not statistically significant hemoglobin Significance of learning. Conclusion: The adverse reactions of bleeding after oral administration of Marvelon oral contraceptives occur less, which can effectively prevent the occurrence of iron deficiency anemia in women of childbearing age.