Mechanisms, clinically curative effects, and antifungal activities of cinnamon oil and pogostemon oi

来源 :中医杂志(英文版) | 被引量 : 0次 | 上传用户:ping_ge
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The anti-fungus mechanisms and curative effects of cinnamon oil and pogostemon oil complexes towards intestinal Candida infections were investigated.We measured the minimal inhibitory concentration (MIC) values of the complexes against Candida using proportionally-diluted test-tube medium,and examined the evolution of the morphology and structures of Candida albicans using scanning electronic microscopy (SEM) and transmission electronic microscopy (TEM).We found that the average MIC values of the complexes against the fungi were 0.064 mg/mL (cinnamon oil),0.032 mg/mL (pogostemon oil) for Candida albicans,0.129 mg/mL (cinnamon oil),0.064 mg/mL (pogostemon oil)for Candida tropicalis,and 0.129 mg/mL (cinnamon oil),0.064 mg/mL (pogostemon oil),for Candida krusei.SEM examination over a 24-48 h period showed that the morphology of Candida albicans cells changed significantly.Irregular hollows appeared on the surfaces,inside organelles were destroyed and the cells burst after treatment.TEM examination over a 48 - 72 h period indicated that the cell walls were damaged,organelles were destroyed and most cytoplasms became empty bubbles.Sixty intestinal Candida-infected patients were treated with a capsule containing cinnamon and pogostemon oil.The curative ratio was 71.67% (43/60),and the improvement ratio was 28.33% (17/60),giving a total ratio of 100%.Thus,the cinnamon oil and pogostemon oil complexes had strong anti-fungus effects against Candida albicans,Candida tropica/is,and Candida krusei.They impacted the morphologyand sub-micro structures ofthe fungus within 48 -72 h,and eventually denatured and killed the cells.The complexes have also shown considerable curative effects to intestinal Candida infections.
其他文献
小儿气管插管运用呼吸机辅助呼吸在临床上十分常见,由危及生命.气管插管拔管前后的有效护理是脱机成败的关键.于小儿喉腔狭窄、喉部粘膜下组织及弹力纤维较疏松、柔软、2010
ICU患者病情危重,变化快,用药复杂,血压监测是ICU患者的重要监测手段,无创血压监测为传统的的测量血压的方法,是通过“断、续、流”原理进行测压的,其简单实用但只能每隔一定
期刊
期刊
OBJECTIVE:To systematically review the benefits of integrated traditional and West medicine therapies based on the Hamilton depression scale (HAMD) following sy
期刊
OBJECTIVE:To systematically evaluate the curative effect of acupuncture on post-stroke depression (PSD).METHODS:The intet was used to retrieve the Wanfang Medic
期刊
OBJECTIVE:To evaluate the therapeutic effects and long-term efficacy of acupuncture for neurogenic dysphagia.METHODS:Subjects with neurogenic dysphagia undergoi