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目的:了解我区药品不良反应(ADR)的发生特点。方法:对我区2008年1月～2009年12月收集到的836例ADR报告,分别从性别、年龄、报告人职业、药品种类、给药途径、涉及器官或系统及临床表现等方面进行统计、分析。结果:医师上报最多,占72.01%;涉及药品以抗感染药居多,占71.16%;给药途径以静脉滴注比例最高,达78.59%;临床表现以皮肤及其附件损害最多,占57.17%。结论:医疗机构和相关部门应加大ADR的监测力度,促进ADR监测工作的全面发展,确保安全、有效、合理用药,提高医疗质量,保证患者的健康。
Objective: To understand the occurrence of adverse drug reaction (ADR) in our district. Methods: A total of 836 ADR cases were collected from January 2008 to December 2009 in our district from the aspects of sex, age, occupation of reporter, drug type, route of administration, organ or system and clinical manifestation ,analysis. Results: Physicians reported the most, accounting for 72.01%. Most of the drugs involved were anti-infectives, accounting for 71.16%. The route of administration was the highest with an infusion rate of 78.59%. The most common manifestation was the skin and its accessories, accounting for 57.17%. Conclusion: Medical institutions and relevant departments should intensify the monitoring of ADR, promote the all-round development of ADR monitoring, ensure safe, effective and rational use of drugs, improve medical quality and ensure patient’s health.