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目的观察并评价中西医结合治疗妊娠期外阴阴道念珠菌病的疗效与不良反应。方法将70例妊娠期外阴阴道念珠菌病的患者随机分为两组,观察组35例采用中药坐浴+克霉唑栓+乳杆菌活菌胶囊治疗,对照组35例采用克霉唑栓+乳杆菌活菌胶囊治疗,治疗前后观察临床表现,并进行妇产科检查及阴道分泌物镜检。结果两组治疗前后临床症状均有改善,但组间比较观察组治愈率优于对照组(p<0.01),用药期间各组对象无任何不良反应,也无畸形胎儿出生。结论中西医结合为妊娠期治疗外阴阴道念珠菌病经济、安全、有效。
Objective To observe and evaluate the efficacy and adverse reactions of integrated traditional Chinese and western medicine in the treatment of vulvovaginal candidiasis during pregnancy. Methods Seventy patients with vulvovaginal candidiasis during pregnancy were randomly divided into two groups. 35 cases in the observation group were treated with traditional Chinese medicine bath + clotrimazole suppository and Lactobacillus live capsule, and 35 cases in control group were treated with clotrimazole suppository + Live Lactobacillus capsule treatment, clinical observation before and after treatment, and obstetrics and gynecology examination and vaginal secretions microscopy. Results The clinical symptoms of both groups were improved before and after treatment, but the cure rate of the observation group was better than that of the control group (p <0.01). No adverse reactions and no birth of deformed fetus were observed in each group during the treatment. Conclusion Integrative Medicine for the treatment of vulvovaginal candidiasis during pregnancy is economical, safe and effective.