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目的探讨原发性肾病综合征复发因素。方法选择147例原发性肾病综合征病例,对其中53例复发者就其治疗方案、疗程及诱发因素进行分析。结果单用泼尼松治疗复发率高(59.26%);泼尼松+环磷酰胺+中药治疗复发率低(23.52%)且治疗缓解间期长;泼尼松治疗诱导缓解期大于10周复发率低;感染是肾病综合征(NS)患者复发最多见诱因。结论选择恰当的治疗方案、足够长的疗程、防治感染、避免劳累、按规范治疗是减少复发的重要环节。
Objective To investigate the recurrence of primary nephrotic syndrome. Methods 147 cases of primary nephrotic syndrome were selected, of whom 53 cases of recurrence were analyzed on their treatment regimen, course of treatment and predisposing factors. Results The recurrence rate was higher with prednisone alone (59.26%). The recurrence rate was lower with prednisone + cyclophosphamide plus traditional Chinese medicine (23.52%) and the treatment was prolonged. Prednisolone treatment induced remission Recurrence rates> 10 weeks are low; infection is the most common cause of relapse in patients with nephrotic syndrome (NS). Conclusion Select the appropriate treatment options, long enough course of treatment, prevention and treatment of infection, to avoid fatigue, according to standard treatment is an important part of reducing recurrence.