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患者女,36岁,农民。因腹泻、便秘交替2个月伴发热3天,于1996年4月8日入院。2个月前患者无明显诱因出现脐周不适,腹泻便秘交替。腹泻时每天排糊状稀便3~4次,不含粘液及脓血,无里急后重,继而2~3天排硬便1次,无明显腹痛、呕吐、便血、发热及盗汗。多次在当地医疗站中药治疗,症状无缓解,头晕、乏力渐加剧。近3天出现发热,体温波动于37.0℃~39.6℃,无四肢关节肿痛,皮疹及皮肤粘膜出血,当地对症治疗无效。发病以来食欲明显减退,体重下降5公斤。患者既往体健,无结核病史。体查:体温37.2℃,脉搏85次/分,呼吸20次/分,血压13/9kPa。贫血貌,消瘦,皮肤粘膜无出血点及皮疹,浅表淋巴结无肿大,巩膜无黄染,咽充血,扁桃体无肿大,齿龈无肿胀渗血,胸骨无压痛,心肺无异常。腹平软,脐左侧可触及约3cm×8cm纵行条索状包块,质地较硬轻压痛,活动度尚可,肝脾肋下未触及,腹水征(-),肠鸣音正常,肛门指诊无异常。实验室及特殊检查:血红蛋白60g/L,白细胞5.2×109/L,中性0.76,淋巴0.23,大单核0.01,血小板200×109/L,网织红细胞0.005,血沉4mm/h,大便常规:红细胞少许,大便隐血(十),尿常规正常,肝肾功能正常,血清白蛋白28g/L,球蛋白24g/L,蛋白电泳γ-球蛋?
Female patient, 36 years old, farmer. Due to diarrhea and constipation, she was admitted to the hospital on April 8, 1996, alternating 2 months with fever for 3 days. Two months before the patient no obvious cause of umbilical discomfort, diarrhea, constipation alternating. Daily diarrhea diarrhea paste 3 to 4 times a day, without mucus and pus and blood, no urgency and weight, followed by 2 to 3 days row hard stool 1 no obvious abdominal pain, vomiting, bloody diarrhea, fever and night sweats. Many times at the local medical station for traditional Chinese medicine treatment, symptoms did not ease, dizziness, fatigue gradually increased. In the past 3 days, fever occurred, and the body temperature fluctuates from 37.0°C to 39.6°C. There was no joint swelling, pain, skin rash, and mucous membrane bleeding. The local symptomatic treatment was ineffective. Appetite has decreased significantly since the onset of illness, with weight loss of 5 kg. The patient was physically fit and had no history of tuberculosis. Physical examination: body temperature 37.2 °C, pulse 85 beats / min, breathing 20 beats / min, blood pressure 13/9kPa. Anemia appearance, weight loss, skin and mucous membranes without bleeding spots and rash, no enlargement of superficial lymph nodes, no sclera yellow stained, pharyngeal congestion, no swelling of the tonsils, gum swelling without bleeding, sternal tenderness, no abnormal heart and lung. Abdominal soft, the left side of the umbilicus can touch about 3cm × 8cm longitudinal cord-like mass, texture harder tenderness, activity is acceptable, liver and spleen is not touched under the ribs, ascites sign (-), bowel sounds normal, There is no abnormality in the anal diagnosis. Laboratory and special examination: hemoglobin 60g/L, white blood cell 5.2×109/L, neutral 0.76, lymphoid 0.23, large mononuclear 0.01, platelet 200×109/L, reticulocyte 0. 005, ESR 4mm/h, stool routine: a little red blood cells, fecal occult blood (ten), normal urine, normal liver and kidney function, serum albumin 28g/L, globulin 24g/L, protein electrophoresis γ-globe?