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消化性溃疡病(PUD)是一具有复发特性的慢性病。经药物治愈后的十二指肠溃疡或胃溃疡经常出现复发。据报道,十二指肠溃疡病人经全量(full-dose)抗溃疡治疗后的12个月中复发率为20～80%。胃溃疡病亦有复发倾向,但确切的复发率目前知道甚少。预防溃疡病的复发,已成为药物治疗中一个重要课题。PUD复发的定义是病人在全量治疗的间歇期或全量治疗以后的低剂量维持治疗中出现溃疡病症状。对于在初次治疗后3～6个月中复发并伴有严重症状和/或更为频繁复发的病人,则需要低剂量的维持治疗,以预防溃疡病复发。一、治疗终止后的溃疡病复发 PUD的复发程度和频率也许与病人处
Peptic ulcer disease (PUD) is a chronic disease with recurrent trait. Recurrence often occurs after duodenal ulcer or gastric ulcer after drug cure. It has been reported that the recurrence rate of patients with duodenal ulcer in the 12 months after full-dose anti-ulcer treatment is 20-80%. Gastric ulcer disease also has a tendency to relapse, but the exact relapse rate is currently poorly understood. To prevent the recurrence of ulcer disease has become an important issue in drug treatment. Recurrence of PUD is defined as the appearance of a canker symptom in patients undergoing low-dose maintenance therapy after the full-dose treatment or after full-dose treatment. For patients who relapse 3 to 6 months after initial treatment with severe symptoms and / or more frequent recurrence, low-dose maintenance therapy is needed to prevent the recurrence of ulcer disease. First, the treatment of ulcer disease after the recurrence of recurrence and frequency of PUD may be at the patient’s office