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早在1968年Berger等对IgA肾病已有了认识。原发性IgA肾病的特点是:①在肾小球系膜中有IgA沉着,同时伴或不伴C_3及其他免疫球蛋白沉着;②在临床上有血尿、蛋白尿,血压中度升高,血清IgA增高(除外肝病、系统性红斑狼疮,过敏性紫癜或其他系统性疾病)。病原免疫复合体 Anedrew等在78例IgA肾病患者中的43.6%检出循环免疫复合体(CIC),CIC大小是9～17 S,其中包含IgA,
As early as 1968 Berger and other IgA nephropathy has been recognized. Primary IgA nephropathy is characterized by: ① in the glomerular mesangial IgA calm, with or without C_3 and other immunoglobulin deposition; ② clinically hematuria, proteinuria, moderate blood pressure, Serum IgA increased (except liver disease, systemic lupus erythematosus, Henoch-Schonlein purpura or other systemic diseases). The pathogenic immune complex Anedrew et al detected circulating immunocomplex (CIC) in 43.6% of 78 IgA nephropathy patients with a CIC size of 9-17 S, which included IgA,