论文部分内容阅读
目的探讨糖类抗原19-9(CA19-9)和癌胚抗原(CEA)检测在恶性腹水中的意义。方法对80例腹水病为分为结核性、非结核良性及恶性腹水3组。罗氏电化学发光仪同步检测腹水CA19-9、CEA。结果恶性腹水CA19-9和CEA明显高于结核性及非结核良性腹水(P<0.01)。CA19-9诊断恶性腹水的敏感性和持异性分别为77.8%和93%,CEA的敏感性和特异性分别为52.8%和93%,二者联合检测敏感性为89.7%、特异性为86.6%。结论CA19-9和CEA对良恶性腹水有鉴别价值,CA19-9诊断恶性腹水的敏感性优于CEA,联合检测可使诊断恶性腹水的敏感性明显增高。
Objective To investigate the significance of detection of carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) in malignant ascites. Methods Eighty cases of ascites were divided into 3 groups: benign and malignant ascites. Roche electrochemical luminometer simultaneous detection of ascites CA19-9, CEA. Results Malignant ascites CA19-9 and CEA were significantly higher than tuberculous and non-tuberculous benign ascites (P <0.01). The sensitivity and specificity of CA19-9 in the diagnosis of malignant ascites were 77.8% and 93%, respectively. The sensitivity and specificity of CEA were 52.8% and 93% respectively. The combined sensitivity and specificity of CA19-9 were 89.7% and 86.6% . Conclusions CA19-9 and CEA have differential value in the diagnosis of benign and malignant ascites. The sensitivity of CA19-9 in diagnosis of malignant ascites is better than that of CEA. The combined detection of CA19-9 and CEA can significantly increase the sensitivity of malignant ascites.