Two new lanostane triterpenoids from Abies sachalinensis

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:anquanke123
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The continuous chemical investigation on the ethyl acetate (EtOAc) soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton.They were identified as 3,4-seco-8- (14→13R)abeo-17,13-friedo-9β-lanosta-4(28),7,14(30),24-tetraen-26,23-olide-23-hydroxy-3-oic acid (1) and 7,14-mariesa- dien-3α-hydroxy-25-methoxy-26-oic acid (2).Structural determination of these compounds were carried out by the spectral studies especially by the two digital (2D)-NMR and high-resolution MS experiences. The continuous chemical investigation on the ethyl acetate (EtOAc) soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton. These were identified as 3,4-seco-8- (14 → 13R) abeo- 17,13-friedo-9β-lanosta-4 (28), 7,14 (30), 24- tetraen- 26,23-olide- 23-hydroxy-3-oic acid Structural determinations of these compounds were carried out by the spectral studies especially by the two digital (2D) -NMR and high-resolution MS experiences.
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