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  5. Chrysophanol localizes in mitochondria to promote cell death through upregulation of mitochondrial c

Chrysophanol localizes in mitochondria to promote cell death through upregulation of mitochondrial c

来源 :中草药：英文版 | 被引量 : 0次 | 上传用户：loveme2001
【摘 要】
：
Objective:Chrysophanol(Chry) displays potent anticancer activity in human cancer cells and animal models,but the cellular targets of Chry have not been fully defined.Herein,we speculated whether mitochondria were a target involved in Chry-induced cytotoxi
【作 者】
：
Yu Xie Ling Zhang Yuan-yuan Li Dian He Li-fang Zheng 
【机 构】
：
SchoolofPharmacy
【出 处】
：
中草药：英文版
【发表日期】
：
2021年2期
【关键词】
：
CHRYSOPHANOL combination therapy MITOCHONDRIA mitochondrial permeability transit 
【基金项目】
：
supported by the Fundamental Research Funds for the Central Universities (Grant No.lzujbky-2018-131),the National Natural Sciences Foundation of China (Grant No.21302079)。
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Objective:Chrysophanol(Chry) displays potent anticancer activity in human cancer cells and animal models,but the cellular targets of Chry have not been fully defined.Herein,we speculated whether mitochondria were a target involved in Chry-induced cytotoxi
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