Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary scl

• 作 者: Tamas Tornai Eszter Palyu Zsuz
• 机 构: InstituteofInternalMedicine,DepartmentofLaboratoryMedicine,InovaDiagnostics,1~（st）DepartmentofPediat
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年29期
• 关键词: 主要 sclerosing 胆管炎 毁坏障碍机能障碍 肠的丰满的酸绑定的蛋白质 Anti-F-actin 抗体 反麦胶蛋白质抗体 Primary scleros
• 基金项目: Supported by Research Grant of National Research Development and Innovation Office,No.K115818/2015/1,János Bólyai Research Scholarship of Hungarian Academy of Sciences to Papp M,the New Nati

AIM To assess the prevalence of a panel of serologic markers that reflect gut barrier dysfunction in a mixed cohort of pediatric and adult primary sclerosing cholangitis（PSC） patients.METHODS Sera of 67 PSC patients [median age（range）: 32（5-79） years, con