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血小板激活因子（Plateletactivatingfacter．PAF）为近年来发现的一种内源性并具有广泛生物学活性的磷脂类介质。业已表明，PAF参与血小板活急性炎症、过敏性哮喘、内毒素血症等病理生理过程。现就PAF的生物学性质，拮抗剂的来源及其临床研究的现状与进展作一综述。1PAF的生物
Platelet activating factor (PAF) is an endogenous and widely bioactive phospholipid mediator found in recent years. It has been shown that PAF is involved in the pathophysiological processes of acute platelet-activating inflammation, allergic asthma, endotoxemia and the like. The biological properties of PAF, the source of antagonists and the status quo and progress of clinical studies are reviewed. 1PAF creature