恶性心包积液的临床处理(附48例分析)

• 作 者: 阮萃才
• 出 处: 中国医学文摘(肿瘤学)
• 发表日期: 2003年01期
• 关键词: 恶性心包积液 腔内化疗 化疗有效率 临床处理 心包穿刺 置管术 心包填塞 生存质量 不良反应

48例中因有心包填塞症状而行心包穿刺置管术19例,并行腔内化疗。首先引流并尽可放尽积液后,于腔内注入DDP 60～80mg、MMC20mg等药物,同时予以地米10mg。5～7d后再次重复治疗。结果:CR 9例,好转8例,无效1例,有效率为89.5%。未行腔内化疗者的全身化疗有效率为34.5%。认为当心包积液量较多时,应首选腔内注药治

In 48 cases, there were 19 cases of pericardiocentesis and catheterization because of the tamponade symptoms and concurrent endovascular chemotherapy. First of all drainage and try to discharge fluid, the cavity into the DDP 60 ~ 80mg, MMC20mg and other drugs, at the same time to rice 10mg. 5 ~ 7d again after repeated treatment. Results: CR 9 cases, 8 cases improved, 1 case ineffective, the effective rate was 89.5%. The rate of systemic chemotherapy in those who did not undergo intracavitary chemotherapy was 34.5%. Beware of fluid package volume should be preferred when the cavity injection drug treatment