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1971～1978年间,对匈牙利东南部地区25648名饮用砷污染的深井水的居民进行了调查(砷的最高浓度超过0.1 mg/L),并以饮低砷水的邻村20836名居民为对照。对所采集的2059份发样(含对照发样230份)进行了评价,结果饮水砷含量与发砷浓度平行,高发砷出现在饮水砷为0.17～0.33 mg/L的地区(略高于国际允许浓度0.05～0.1 mg/L)。污染区儿童发砷最高浓度超过3 mg/kg。在饮用砷污染水的人中未发现严重的血管障碍性疾病如黑脚病。癌症发生率、外周神经病及末梢血管障碍在接触砷的成人与对照人群中均无明显差异。据报道,在接触砷等环境污染物的人群中,因显性点突变及染色体畸变发生率升高,预期的自然流产率及死产事都高。1980～1987年间,作者对两地区的大量的活产、自然流产及死产做了对比分析。结果表明,在高、低砷污染区分别有5218例及2112例活产、363例及108例自然流产以及40例
Between 1971 and 1978, a survey of 25,648 inhabitants of deep-water arsenic-contaminated water in the southeastern part of Hungary (with arsenic concentrations exceeding 0.1 mg / L) was used, compared with 20,836 residents of neighboring villages that drink low levels of arsenic. The collected samples of 2059 samples (including 230 samples of control samples) were evaluated. As a result, the arsenic content of drinking water was in parallel with that of arsenic, and the arsenic content of drinking water was in the range of 0.17-0.33 mg / L arsenic in drinking water Allowed concentration of 0.05 ~ 0.1 mg / L). The highest concentration of arsenic in children in contaminated areas exceeds 3 mg / kg. No serious vascular disorder such as blackfoot disease was found in those who consumed arsenic-contaminated water. The incidence of cancer, peripheral neuropathy and peripheral vascular disorders were not significantly different between adults and control subjects exposed to arsenic. It is reported that in people exposed to environmental pollutants such as arsenic, the expected spontaneous abortion rate and stillbirth are high due to the increased incidence of dominant point mutations and chromosomal aberrations. Between 1980 and 1987, the authors compared and analyzed the large number of live births, spontaneous abortions and stillbirths in the two regions. The results showed that 5218 and 2112 live births, 363 and 108 cases of spontaneous abortion and 40 cases of spontaneous abortion in high and low arsenic-contaminated areas