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先天性左向右分流心脏病患儿如果未及时治疗,将会发展为肺动脉高压。本综述概述肺动脉高压发生病因、发病机制、诊断和治疗方法。先天性心脏病继发肺动脉高压可通过手术或介入治疗,如果发展到重度肺动脉高压阶段只有通过心肺移植治疗。高危患儿应常规应用超声心动图和心电图来辅助诊断。新的诊断方法和治疗药物的出现,为肺动脉高压患儿治疗带来了希望。
Congenital left-right shunt children with heart disease if not treated, will develop into pulmonary hypertension. This review summarizes the etiology, pathogenesis, diagnosis, and treatment of pulmonary hypertension. Pulmonary hypertension secondary to congenital heart disease can be treated surgically or by intervention and only through cardiopulmonary transplantation if it develops into severe pulmonary hypertension. High-risk children should routinely use echocardiography and electrocardiogram to aid diagnosis. The emergence of new diagnostic methods and therapeutic drugs has brought hope for the treatment of children with pulmonary hypertension.