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对２３例小儿肝母细胞瘤的临床病理学进行了研究，并分析了病理学改变与预后的关系。本组肿瘤均为手术切除标本，用组织化学ＨＥ染色和免疫组化ＡＦＰ检测。结果表明，该肿瘤病理形态特点为瘤体大，最大直径４５ｃｍ；主要成分为胚胎性肝上皮组织，部分病例有胚胎性或较成熟的间叶组织。肿瘤发生在肝左叶或边缘部者预后较好，瘤体大或多结节型者预后差；胎儿型和混合型预后好，未分化型预后差；肝脏血液循环丰富，肝母细胞瘤生长速度快，易侵袭破坏血管发生血行转移，这是影响其预后的重要因素。
The clinical pathology of 23 cases of hepatoblastoma in children was studied, and the relationship between pathological changes and prognosis was analyzed. This group of tumors were surgical resection specimens, histochemical HE staining and immunohistochemical AFP detection. The results showed that the pathological features of the tumor were large tumors with a maximum diameter of 45 cm. The main components were embryonic liver epithelial tissues, and in some cases embryonic or mature mesenchymal tissues. Tumors occur in the left lobe of the liver or the margins of the better prognosis, tumor size or nodules were poor prognosis; fetal and mixed type of good prognosis, undifferentiated poor prognosis; liver blood circulation rich, hepatoblastoma growth Fast, easy invasion and destruction of blood vessels hematogenous metastasis, which is an important factor affecting the prognosis.