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对黄绿蜜环菌生物合成的天麻素进行抗炎及免疫调节活性探讨。试验结果表明,生物合成的天麻素对小鼠耳廓肿胀和小鼠肉芽肿有明显的抑制作用,抗炎效果很好。在碳廓清试验中,天麻素能够较显著地提高小鼠碳廓清指数和吞噬指数。在小鼠淋巴细胞转化试验中,天麻素促进了淋巴细胞的增殖。对NK细胞影响试验中,天麻素能够明显提高靶细胞的吞噬能力,具有很好的免疫调节作用。
To investigate the anti-inflammatory and immunomodulatory activities of gastrodin from bioconjugal of Armillaria yellow globules. The results showed that the biosynthesis of gastrodin mouse ear swelling and mouse granuloma significantly inhibited the anti-inflammatory effect is very good. In the carbon clearance test, gastrodin can significantly improve the mouse carbon clearance index and phagocytic index. Gastrodin promotes lymphocyte proliferation in mouse lymphocyte transformation assays. In NK cell test, gastrodin can obviously improve the phagocytosis of target cells and has a good immunomodulatory effect.