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目的:调查分析临床麻醉性镇痛药的应用情况,促进合理用药。方法:统计2013年我院麻醉性镇痛药应用情况,包括使用量、销售金额、使用科室及用途等,同时进行处方点评,分析用药合理性。结果:我院以硫酸吗啡缓释片、枸橼酸芬太尼注射液、盐酸布桂嗪注射液用药频度(DDDs)最大。芬太尼注射液及盐酸布桂嗪注射液主要用于手术镇痛;硫酸吗啡缓释片则主要用于癌症等中重度疼痛患者的口服止痛。多数药物销售金额/DDDs排序比接近于1,表示同步性良好。麻醉性镇痛药的主要用途是手术麻醉辅助用药及术后镇痛、癌症镇痛、普通外伤镇痛等。使用科室主要以外科、肿瘤科、妇产科、急诊科为主。在用药合理性方面,用药剂量、频次等方面仍存在问题,还需改进。结论:对于癌痛患者的镇痛治疗,还需临床医师严格按照《癌症三阶梯止痛指导原则》使用麻醉性镇痛药,提高用药合理性。
Objective: To investigate the clinical application of narcotic analgesics and to promote the rational use of drugs. Methods: Statistics on the application of narcotic analgesics in our hospital in 2013, including the usage, sales amount, use of departments and purposes, etc., at the same time for prescription reviews, analysis of drug use rationality. Results: In our hospital, Morphine sulfate sustained-release tablets, fentanyl citrate injection and buzine hydrochloride injection had the highest frequency of DDDs. Fentanyl injection and buprofen hydrochloride injection is mainly used for surgical analgesia; morphine sulfate sustained-release tablets are mainly used for oral pain relief in patients with moderate-severe pain such as cancer. Most drug sales amount / DDDs rank close to 1, indicating good synchronicity. The main purpose of narcotic analgesics is surgical anesthesia auxiliary medication and postoperative analgesia, cancer pain, general trauma analgesia. The main use of surgical departments, oncology, obstetrics and gynecology, emergency department based. The rationality of medication, the dosage, frequency, etc. there are still problems, but also need to be improved. Conclusion: For the analgesic treatment of patients with cancer pain, clinicians are required to use narcotic analgesics in strict accordance with the Guiding Principles of Three-Step Cancer Pain Relief to improve the rationality of medication.