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肿瘤耐药逆转剂研究新进展陆东东肿瘤细胞对多种化疗药物产生交叉抗药性是造成肿瘤化疗失败的主要原因。多药耐药（ＭＤＲ）的发生机制十分复杂，其中多药耐药基因编码的Ｐ－糖蛋白（ＰｇＰ）高表达是多药耐药的主要机制。人类ｍｄｒ１基因编码的ＰｇＰ是一种能量依赖性“...
Advances in Research of Drug Resistance Reversal Agents Lu Dongdong’s tumor cell cross-resistance to various chemotherapeutic drugs is the main cause of cancer chemotherapy failure. The mechanism of multidrug resistance (MDR) is very complicated. The high expression of P-glycoprotein (PgP) encoded by multidrug resistance gene is the main mechanism of multidrug resistance. The PgP encoded by the human mdr1 gene is an energy-dependent...