论文部分内容阅读
目的通过回顾研究,比较支撑架植入术后放化疗和非放化疗对晚期食道癌患者生存率的影响。方法1996年2月至1999年1月,37例晚期食道癌患者因食道癌引起的吞咽困难行食道支撑架植入术。术前进行临床和影像学检查。对植入术前后的吞咽能力进行评分,对术后放化疗组生存率的影响进行分析。结果34例病人的吞咽困难症状得到改善,4例病人手术中需植入2个支撑架,其中2例因病变部位长,2例支撑架植入位置不良,8例病人平均随访时间125.25士28.07天,由于术后吞咽困难加重需植入第二个支撑架,术后37例平均生存时间175.27士77.13天,进行术后放化疗组病人(n=17)生存期相对延长,诊断后平均生存期261.52士58.59天,较非放化疗组平均生存时间为144.3土41.64天(P<0·001)。结论晚期食道癌支撑架植入术结合术后的放化疗可以改善病人的生存时间。
Objective To compare the effects of radiotherapy, chemotherapy and non-radiotherapy after stent implantation on the survival rate of patients with advanced esophageal cancer. Methods From February 1996 to January 1999, 37 patients with advanced esophageal cancer underwent esophageal stent implantation due to dysphagia caused by esophageal cancer. Preoperative clinical and radiological examinations. The swallowing ability before and after implantation was scored, and the effect of postoperative radiotherapy and chemotherapy on the survival rate was analyzed. Results The symptoms of dysphagia were improved in 34 patients. Two stents were implanted in the operation in 4 patients. Among them, 2 were due to a long lesion, 2 stents were poorly implanted, and 8 patients had an average follow-up time of 125.25±28. .07 days, due to the need to implant a second support frame after the increase in postoperative dysphagia, the average survival time of 37 patients was 175.27 persons and 77.13 days after surgery. The patients with postoperative radiochemotherapy (n=17) had relatively similar survival time. Prolonged, the average survival time after diagnosis was 261.52 ± 58.59 days, compared with non-chemotherapy group, the average survival time was 144.3±41.64 days (P<0.001). Conclusion The stent implantation of advanced esophageal cancer combined with postoperative radiotherapy and chemotherapy can improve the patient’s survival time.