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在化学领域中,手性是一个十分重要的概念,人们已充分认识到各种天然化合物及合成药物的各种对映体有着不同的生物活性。由于各种各样酶的立体选择作用,在生物体内形成一种特殊的手性环境。同时,不少合成药物或农药其中间体或其本身均具有手性。很多从天然产物衍变的杀虫剂多具有手性结构,它们的生物活性与某异构体的构型密切相关。就拟除虫菊酯类杀虫剂而言,其对映异构的选择性源于昆虫神经系统中作用部位的手性特
In the field of chemistry, chirality is a very important concept. It has been well recognized that various enantiomers of various natural and synthetic drugs have different biological activities. Due to the stereoselective effect of various enzymes, a special chiral environment is formed in the organism. At the same time, many synthetic drugs or pesticides intermediates or their own are chiral. Many of the pesticides that are derived from natural products have more chiral structures and their biological activities are closely related to the configuration of some isomers. For pyrethroid insecticides, their enantiomeric selectivity results from the chirality of the site of action in the insect nervous system