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心脏移植不仅已成为一种医学现实,而且是一种可以接受的晚期心脏病的治疗方法。尽管免疫抑制已有明显发展,但受体对移植心脏的排斥仍是需要克服的主要障碍之一。移植免疫学:免疫系统通过免疫应答对异体组织产生反应,免疫应答是由传入的免疫支引起的一系列反应。这些传入支包括T辅助细胞、抗原和一些介质。免疫应答由下列组成:①异体组织的非已识别;②免疫活性细胞的增殖:③效应支的活化。抗原是可激发免疫应答的糖蛋白。免疫应答可产生耐
Heart transplantation has not only become a medical reality, but also an acceptable treatment for advanced heart disease. Although immunosuppression has evolved significantly, the rejection of transplanted heart by the recipient remains one of the major obstacles to be overcome. Transplant Immunology: The immune system responds to allogeneic tissue through an immune response, a series of reactions initiated by the incoming immune branch. These afferent branches include T helper cells, antigens, and some mediators. The immune response consists of the following: non-identified allogeneic tissue; proliferation of immunocompetent cells; activation of effector branches. Antigens are glycoproteins that can elicit an immune response. Immune response can produce resistance