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以智能为主要特征的新科技革命促使不同学科飞速发展、交互融通，各类颠覆性理念和技术的不断涌现使医学发展模式由经验医学、循证医学、精准医学等模式逐步向智慧医学转变。在此背景下，骨科学的发展壮大也必将借助新一代信息技术、先进制造技术、新材料技术等进行诊疗理念、治疗方法和预后预测的智慧化变革。完善学科知识体系，探索骨科学“智慧”发展模式，是当今骨科医生和研究人员的使命与职责。本文从“智慧”的内涵出发，通过典型智能技术影响骨科学发展的若干方面，逐步构建现代科技赋能的最优化“智慧骨科”生态体系。“,”Characterized by intelligence, the new revolution of science and technology accelerates the high-speed development of different academic disciplines and promotes inter-change of ideas from each other. Thanks to the constantly emerging of different types of subversive ideas and techniques, the medicine model has been transformed gradually from experience medicine, evidence-based medicine and precise medicine to smart medicine and wisdom-based medicine. Under this background, the rapid development of orthopaedics is based on intelligent technologies, such as new information technology, advanced manufacturing technology, new materials technology, etc. Furthermore, all these changes also facilitate the wisdom transformation of clinical concepts, treatment methods and prognostic prediction of orthopaedics. Therefore, optimization of orthopaedic knowledge system and exploration of a wisdom-oriented development model are the mission and responsibility of the current orthopaedic physicians and researchers. In this paper, the connotation of wisdom is introduced, and several orthopaedic areas of application of novel intelligent technologies are overviewed. Hopefully through this way, an optimized wisdom orthopaedic ecosystem can be constructed step-by-step after being empowered by these cutting-edge technologies and giving full play to their advantages.