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目的:探讨三维适形放射治疗上段食管癌的疗效。方法:回顾性分析37例上段食管癌患者接受三维适形放射治疗(2Cy/次,5次/周,总剂量66～68Cy,6～7周完成)的疗效。结果:1、2、3年局部控制率分别为87.9%、75.8%、62.2%;1、2、3年生存率分别为97.3%、81.1%、56.8%,急性放射反应主要是急性放射性食管炎和急性放射性气管炎,多为1、2级。多因素分析结果显示原发肿瘤的长度、分期和锁骨上淋巴结转移是影响预后的主要因素。结论:三维适形放射治疗是治疗上段食管癌的有效治疗方法。
Objective: To investigate the effect of three-dimensional conformal radiotherapy on upper esophageal cancer. Methods: A retrospective analysis of 37 patients with upper esophageal cancer received three-dimensional conformal radiotherapy (2Cy / times, 5 times / week, the total dose of 66 ~ 68Cy, 6 to 7 weeks to complete the curative effect. Results: The local control rates at 1, 2 and 3 years were 87.9%, 75.8% and 62.2% respectively. The 1-, 2-, and 3-year survival rates were 97.3%, 81.1% and 56.8% respectively. The acute radiation response was mainly acute esophagitis And acute radiation tracheitis, mostly 1, 2. Multivariate analysis showed that primary tumor length, staging and supraclavicular lymph node metastasis were the main factors affecting the prognosis. Conclusion: Three-dimensional conformal radiotherapy is an effective treatment for upper esophageal cancer.