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在一项随访研究中,对HBsAg阳性急性病毒性肝炎、慢性迁延性肝炎(CPH)、慢性活动性肝炎(CAH)病人进行了一系列血清抑制因子(SIF)的研究。血清抑制因子的抑制活性以抑制指数(即正常淋巴细胞在被试血清中用植物血凝素(PHA)诱导产生的淋转与在对照血清中用PHA诱导产生的淋转的比值)来表示。正常血清的平均指数为0.95,指数低于0.70时为有抑制活性。结果:18名HBsAg阳性急性病毒性肝炎病人的第1周血清都显著抑制PHA诱导的正常淋巴细胞的转化,平均指数为0.25,
In a follow-up study, a series of serum inhibitors of inhibition (SIF) were studied in patients with HBsAg-positive acute viral hepatitis, chronic persistent hepatitis (CPH) and chronic active hepatitis (CAH). Inhibitory activity of serum inhibitors was expressed as the inhibition index (ie, the ratio of lymphocytes induced by phytohemagglutinin (PHA) in normal sera to normal lymphocytes and the PHA-induced lymph node metastasis in control sera). The average index of normal serum was 0.95, while the index below 0.70 was inhibitory activity. Results: The serum of 18 HBsAg-positive acute hepatitis patients in the first week significantly inhibited PHA-induced normal lymphocyte transformation with an average index of 0.25,