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[目的]探讨胆囊癌患者术中检测第13组淋巴结冰冻病理结果对患者手术术式选择及与术后生存期的关系。[方法]分析行胆囊癌手术切除的49例患者的胆囊癌病理结果,常规对第13组淋巴结进行术中冰冻病理活检,根据其结果决定术中淋巴结清扫范围,并进行生存期分析。[结果]术中冰冻病理结果提示有19例患者并发有第13组淋巴结转移,虽然进行了相应范围的淋巴结清扫,其中位生存期仍较第13组淋巴结未出现转移的患者缩短(8.5个月vs 13.0个月,t=10.514,P<0.001)。第13组淋巴结有转移患者的中位生存期与患者的肿瘤大小、分化程度相关(P<0.05)。[结论]第13组淋巴结术中冰冻病理检查对指导此类患者的手术切除范围及判断胆囊癌患者预后有一定意义。
[Objective] To investigate the relationship between operation procedure selection and postoperative survival of 13 patients with gallbladder carcinoma detected by intraoperative lymphadenectomy. [Methods] The pathological results of gallbladder carcinoma in 49 patients with gallbladder carcinoma were analyzed. Intraoperative lymphadenectomy was performed on group 13 lymph nodes. The range of lymph node dissection was determined according to the results and the survival period was analyzed. [Results] The intraoperative frozen pathological findings suggested that 19 patients had lymph node metastasis in group 13, and the median survival time was shorter than that in group 13 without lymph node metastasis (8.5 months), although a corresponding range of lymph node dissection was performed vs 13.0 months, t = 10.514, P <0.001). The median survival of patients with lymph node metastasis in group 13 correlated with tumor size and differentiation (P <0.05). [Conclusion] The pathological examination of frozen tissue in group 13 lymph node dissection has certain significance in guiding the surgical resection scope and prognosis of patients with gallbladder cancer.