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目的检测丙肝患者尿液中HCV－IgG，协助HCV病原诊断。方法采用酶联免疫法检测丙肝患者50例、健康人20例及同期住院的乙肝和伤寒患者各20人的尿液标本，进行对照观察，将测定值以-x±s表示。用t检验分析结果。结果50例丙肝患者尿标本吸光度（OD）值为0．598±0．037；40例非丙肝患者尿液标本OD值为0．067±0．048，两组比较有权显著性差异（P＜0．001）。结论尿液HCV－IgG检测可作为丙肝病原诊断的另一途径。并对临床判断HCV相关肾病的肾损伤严重程度有实用价值。
Objective To detect HCV-IgG in urine of hepatitis C patients and assist in the diagnosis of HCV pathogens. Methods Urine specimens from 50 hepatitis C patients, 20 healthy individuals and 20 hospitalized patients with hepatitis B and typhoid fever in the same period were detected by enzyme-linked immunosorbent assay (ELISA). The measured values were expressed as -x ± s. T test to analyze the results. Results The urine OD value of 50 cases of hepatitis C patients was 0.598 ± 0.037. The OD value of urine samples from 40 cases of non-hepatitis C patients was 0.067 ± 0.048, and the difference was significant (P <0.001). Conclusion The urine HCV-IgG test can be used as another way to diagnose hepatitis C pathogens. And has practical value in judging the severity of renal injury in HCV-related nephropathy clinically.