Perfluoroalkanosulfonyl fluoride: A useful reagent for dehydration of aldoximes to nitriles

• 作 者: Zhao-Hua Yan Huan Tian Dong-Dong Hong-Ai Jin Wei-Sheng Tian
• 机 构: College of Chemistry, Nanchang University,Shanghai Institute of Organic Chemistry, Chinese Academy o
• 出 处: Chinese Chemical Letters
• 发表日期: 2016年01期
• 关键词: fluoride dehydration reagent smoothly aromatic carboxylic equiv chemicals esters

The reaction of a variety of aldoximes with perfluoroalkanosulfonyl fluoride in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene(DBU) in dichloromethane smoothly generated the corresponding nitriles in 70%–95% yields.

The reaction of a variety of aldoximes with perfluoroalkanosulfonyl fluoride in the presence of 1,8-diazabicyclo [5.4.0] undec-7-ene (DBU) in dichloromethane smoothly generated the corresponding nitriles in 70% -95% yields.