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目的 通过选择适宜的洗胃方法 ,减少中毒病人的毒素吸收 ,从而提高中毒病人初始抢救的效果。方法 经食管向一组DDV中毒威斯特大鼠胃内灌入活性碳混悬液与另一组不做处理中毒大鼠的对比观察 ,对测定的不同时段血中的胆碱酯酶活力 ,进行了比较分析。结果 测得的胆碱酯酶活力比较 ,在灌入毒剂 2 0min和 3h后差异不显著 ,2d和 3d后差异显著。结论 说明活性碳胃内灌注可以减少有机磷毒物的吸收 ,提高初始抢救的效果。
Objective To reduce the toxin absorption of poisoning patients by choosing the appropriate method of gastric lavage so as to improve the initial rescue effect of poisoned patients. Methods A group of DDV intoxicated Wistar rats were intragastrically infused with activated carbon suspension and another group of untreated poisoned rats. The cholinesterase activity in blood was measured at different time points A comparative analysis. Results The measured cholinesterase activity was not significantly different at 20 minutes and 3 hours after perfusion with the agents, and significant differences were observed after 2 and 3 days. Conclusions The intragastric infusion of activated carbon can reduce the absorption of organophosphate poisons and improve the initial rescue effect.