Role of TGF-βl Signaling in Heart Valve Calcification Induced by Abnormal Mechanical Stimulation in

• 作 者: Xing-jian HU Wen-cong-hui WU N
• 机 构: DepartmentofCardiovascularSurgery,DepartmentofGastroenterology
• 出 处: 当代医学科学(英文)
• 发表日期: 2018年5期
• 关键词: VALVE CALCIFICATION ABNORMAL mechanical STIMULATION BIOREACTOR TGF-β1 signal pat
• 基金项目: This work was supported by the National Natural Science Foundation of China (No.81400290).

A tissue engineering model of heart valve calcification induced in a bio-reactor was established to evaluate the calcification induced by abnormal mechanical stimulation and explore the underlying molecular mechanisms.Polyethylene glycol (PEG)-modified de