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利用敏感性及特异性均较强的间接血凝方法(IHA)与间接免疫荧光方法(IIFA)对临床诊断为先天性感染的新生儿脑病、肝炎、肺炎等患儿132例进行血清弓形体IgM、IgG抗体的定量测定,阳性病例部分母血也进行同样测定,结果证实弓形体病因约占6.82％(9/132),除表明弓形体感染导致中枢神经系统与肝脏的损害情况与国内外报道相符外,还特别指出先天性弓形体肺炎问题应引起注意。对被检血也进行了巨细胞病毒、疱疹病毒、风疹病毒等宫内感染中相关病毒特异性抗体检测,说明与病毒合并感染情况。
Thirty-two neonates with neonatal encephalopathy, hepatitis, pneumonia and other clinically diagnosed congenital infections were subjected to indirect hemagglutination (IHA) and indirect immunofluorescence (IIFA) with high sensitivity and specificity. Serum Toxoplasma IgM , IgG antibody quantitative determination, the positive case part of the maternal and blood also carried out the same determination, the results confirmed that the cause of toxoplasmosis accounted for about 6.82% (9/132), in addition to that toxoplasmosis caused central nervous system and liver damage and domestic and foreign reports In line with, but also pointed out that congenital toxoplasmitis should pay attention. The blood was also tested for cytomegalovirus, herpes virus, rubella virus and other intrauterine infection-related virus-specific antibody test to illustrate the merger with the virus infection.