论文部分内容阅读
目的探讨女性代谢综合征(MS)患者高尿酸血症(HUA)的患病情况及相关危险因素。方法对619例女性MS患者进行问卷调查及实验室检查,以血尿酸(UA)<360μmol/L者为单纯MS组,UA≥360μmol/L者为MS合并HUA组,比较2组检测指标差异,采用logistic回归分析HUA危险因素。结果女性MS患者HUA患病率为12.44%;MS合并HUA组年龄、TC、TG、Cr均高于MS组,出现血脂异常、高血压的比例明显高于MS组;年龄增加(OR=2.459)、高TG(OR=1.809)、高TC(OR=1.741)、饮酒史(OR=5.389)是HUA的危险因素。结论合并HUA女性MS患者脂代谢紊乱较为严重,年龄增加、高TG、高TC、饮酒史是女性MS患者出现HUA的危险因素。
Objective To investigate the prevalence and risk factors of hyperuricemia (HUA) in women with metabolic syndrome (MS). Methods A total of 619 female MS patients were investigated by questionnaires and laboratory tests. MS patients with serum uric acid (UA) <360μmol / L and MS with UA≥360μmol / L were enrolled in this study. The differences between the two groups were compared. Logistic regression analysis of risk factors for HUA. Results The prevalence of HUA in female MS patients was 12.44%. The age, TC, TG and Cr in MS patients with HUA were significantly higher than those in MS patients. The prevalence of dyslipidemia and hypertension was significantly higher in MS patients than in MS patients (OR = 2.459) , High TG (OR = 1.809), high TC (OR = 1.741), drinking history (OR = 5.389) were the risk factors of HUA. Conclusions MS patients with HUA complicated with lipid metabolism disorder are more serious. The increase of age, high TG, high TC and alcohol consumption are the risk factors of HUA in female MS.