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细胞凋亡受阻在肿瘤的发生、发展中发挥着重要作用。凋亡是一个生理性的细胞自我毁灭过程,在胚胎发育,生物体内环境的稳定及多细胞生物防御外在及内在伤害等方面均起着重要的作用。凋亡过程的紊乱,可能与许多疾病的发生有直接或间接的关系,如肿瘤、自身免疫病、神经退行性病变
Inhibition of apoptosis in tumor occurrence and development play an important role. Apoptosis is a physiological process of cell self-destruction, plays an important role in embryonic development, the stability of the environment in vivo and the external and internal damage of multicellular biological defense. The disorder of apoptosis process may have a direct or indirect relationship with many diseases such as tumor, autoimmune disease, neurodegenerative diseases