论文部分内容阅读
肥胖一直被认为对骨骼发育有保护作用，但是近年来研究发现肥胖会影响骨骼的代谢与发育，肥胖者发生骨折、骨质疏松等骨骼疾病的风险明显增加。大量研究表明，肥胖会导致骨钙素、甲状旁腺激素、维生素D以及血总Ⅰ型胶原羧基端延长肽和Ⅰ型胶原蛋白羧基端肽等骨代谢相关激素产生不同程度的变化，而这几种激素的变化也会影响糖脂的代谢。骨代谢与糖脂代谢之间的相关性还需要进一步的研究。“,”Obesity has been recognized to have a protective effect on bone development,but in recent years, studies have found that obesity has detrimental effect on the bone metabolism and development of sev-eral hormones related to common bone metabolism.Obesity significantly increases the risks for fracture,osteo-porosis and other bone diseases.A lot of studies have shown obesity can lead to various degrees of changes of hormones related to common bone metabolism,such as osteocalcin,parathyroid hormone,Vitamin D, procol-lagen type Ⅰ amino propeptide and cross-linked telopeptides of type Ⅰ collagen, etc, such changes will impact on glucolipid metabolism in different ways.The relationship between the glucolipid metabolism and bone metabolism needs further research.