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目的:及时了解承德市流感病毒优势株的变化,分析预测流感流行的趋势和特点,为流感防治提供科学依据。方法:2009年5月-2010年10月,对疑似咽拭子标本采用荧光PCR法(realtim ePCR)检测,使用SPSS分析软件进行数据统计分析。结果:2009年第38周全市流感病例突然增多,出现第一次高峰,就诊比例达14.56%(517/3551),到第45周出现第二次高峰,就诊比例达到43.41%(1638/3773)。2009年5月-2010年8月以甲(A)H3型(H3 N2)为优势毒株,9月-12月以甲(A)H1N1亚型为优势毒株,2010年1月-2010年3月主要流行株是乙型(B),9月-10月主要是甲(A)H3型(H3N2)。结论:加强流感样监测,对控制疫情的发生、发展起到至关重要的作用。
Objective: To keep abreast of the changes of predominant strains of influenza virus in Chengde City, to analyze and forecast the trends and characteristics of influenza epidemic, and to provide a scientific basis for the prevention and treatment of influenza. Methods: From May 2009 to October 2010, the suspected throat swab samples were detected by real-time PCR and analyzed by SPSS software. Results: In the 38th week of 2009, the number of flu cases increased sharply in the city with the first peak reaching 14.56% (517/3551), the second peak appeared in the 45th week, and the treatment rate reached 43.41% (1638/3773) . From May 2009 to August 2010, A strain H3 H3 was the dominant strain, and A strain H1N1 subtype was the dominant strain from September to December 2010. The main epidemic strain in March was type B (B), while September-October was mainly type A (H3) H3. Conclusion: Enhancing the monitoring of influenza-like substance plays a crucial role in controlling the occurrence and development of the outbreak.