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目的:探究结核病患者在抗结核治疗过程中出现的不良反应,为临床治疗提供准确依据。方法:选取我院2012年5月-2014年3月门诊及住院部100例结核病患者作为研究对象,按照年龄不同分为对照组(年龄<55,n=30)和观察组(年龄>55,n=70),观察两组患者在抗结核治疗中出现的各种不良反应。结果:两组患者均出现各种不同的不良反应,肝功损伤比较χ2=5.6454(p=0.0175),肾功损伤比较χ2=4.7143(p=0.0299),消化道不适比较χ2=4.5294(p=0.0333),p<0.05,差异具有统计学意义。结论:抗结核药物容易导致不良反应,应根据病人自身情况,合理选择药物进行治疗,尤其是高龄患者,更应注意安全合理用药。
Objective: To explore the adverse reactions of tuberculosis patients during anti-TB treatment and provide an accurate basis for clinical treatment. Methods: A total of 100 tuberculosis patients from outpatient department and inpatient department of our hospital from May 2012 to March 2014 were selected as study subjects and divided into control group (age <55, n = 30) and observation group (age> 55, n = 70). All kinds of adverse reactions in anti-tuberculosis treatment were observed in two groups of patients. Results: A variety of adverse reactions occurred in both groups, with χ2 = 5.6454 (p = 0.0175), renal damage (χ2 = 4.7143) and digestive tract discomfort χ2 = 4.5294 0.0333), p <0.05, the difference was statistically significant. Conclusion: Anti-TB drugs easily lead to adverse reactions, should be based on the patient’s own situation, the rational choice of drugs for treatment, especially in elderly patients, but should pay attention to safe and rational use of drugs.