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目的探讨经尿道电切联合吡柔比星膀胱灌注治疗腺性膀胱炎的临床效果。方法将2008年-2013年7月我院87例腺性膀胱炎患者随机分为观察组52例、对照组35例,对照组接受常规手术,观察组同时给予吡柔比星膀胱灌注联合治疗,比较两组临床疗效及不良反应。结果观察组总有效率明显高于对照组(P<0.05),膀胱刺激征、血尿发生率高于对照组(P<0.05);两组排尿困难、尿外渗等并发症发生率无统计学差异(P>0.05)。随访1年,观察组治愈率高于对照组、复发率低于对照组(P<0.05),未出现癌变病例。结论经尿道电切联合吡柔比星膀胱灌注治疗腺性膀胱炎具有良好疗效,且安全性高,复发率低。
Objective To investigate the clinical effect of transurethral resection combined with pirarubicin in the treatment of cystitis glandularis. Methods A total of 87 patients with glandular cystitis in our hospital from 2008 to July 2013 were randomly divided into observation group (n = 52) and control group (n = 35). The control group received routine surgery, while the observation group received pirarubicin combined with intravesical instillation. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The incidence of bladder irritation and hematuria in the observation group was significantly higher than that in the control group (P <0.05). The complication rates of dysuria and urinary exudation in the two groups were not statistically significant Difference (P> 0.05). Followed up for 1 year, the cure rate of the observation group was higher than that of the control group, and the recurrence rate was lower than that of the control group (P <0.05). No canceration occurred. Conclusion Transurethral resection combined with pirarubicin bladder cystitis treatment of glandular cystitis has a good effect, and high safety, low recurrence rate.