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我院自一九八一年开始胆石间质观察及进行以溶解胆石问质为目标的溶石研究。经过多种方法对胆石间质从定性到定量的分析,认为胆石间质是以糖蛋白为主的粘液物质,在此基础上筛选出木瓜蛋白酶、薄荷油等配制的溶石药剂,经30份胆石标本的实际研究,全部溶解率为67.7％,大部溶解率为32.2％,取得良好效果。 一、胆石间质观察的方法与结果:自1981～1985年先后采用胆石切片显微镜观察,PAS. Alcian blue染色、电镜超薄切片、
In 1981, we observed gallstone interstitials in our hospital and conducted a study on the dissolution of gallstones. After analysis of qualitative and quantitative analysis of gallstone interstitial by various methods, it is considered that gallstone interstitial substance is a glycoprotein-based mucin substance, and based on this, a solution of the dissolved stone preparations such as papain and peppermint oil is selected. The actual study of gallbladder specimens, the overall dissolution rate was 67.7%, most of the dissolution rate was 32.2%, and achieved good results. First, the method and results of observation of gallstone interstitial: From 1981 to 1985 have been observed using gallstone microscopy, PAS. Alcian blue staining, ultrathin electron microscopy,