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产科新药——硫酸普拉酮钠在扬州制药厂研制成功,经卫生部批准为二类新药,在该厂独家生产。 1.药代动力学 妊娠末期孕妇一次静注本品后15min,血药浓度为给药前的3.4～13.6倍,主要分布于肝、肾、肺和消化道,给药后96小时内经尿粪排出。 2.临床治疗效果 对临床确诊孕周38～39~(+6),肛查Bishop评分≤2′;孕周≥40,Bishop评分≤4′,且无产兆者,静注本
Obstetric new drug - sodium pram sulfate sulfate was successfully developed in Yangzhou Pharmaceutical Factory, approved by the Ministry of Health as two types of new drugs, the exclusive production plant. 1. Pharmacokinetics Pregnant women at the end of pregnancy once intravenous injection of this product 15min, plasma concentration of 3.4 to 13.6 times before administration, mainly in the liver, kidney, lung and digestive tract, within 96 hours after administration of urine excrement discharge. 2. The clinical effect of clinically diagnosed at 38 ~ 39 ~ (+6) gestational weeks, anal Bishop score ≤ 2 ’; gestational age ≥ 40, Bishop score ≤ 4’, and no evidence of aorbital, intravenous